Bioengineer.org

Bioengineer.org: Columbia University to explore impact of genetic information of autism on families, individuals

Bioengineer.org: Columbia University to explore impact of genetic information of autism on families, individuals

NEW YORK, NY (September 28, 2018) — The Center for Research on the Ethical, Legal and Social Implications of Psychiatric, Neurologic, and Behavioral Genetics at Columbia University Irving Medical Center (CUIMC) will bring its expertise to bear on exploring the effects of new genetic knowledge on individuals with autism spectrum

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Bioengineer.org: Study of protein 'trafficker' provides insight into autism and other brain disorders

Bioengineer.org: Study of protein 'trafficker' provides insight into autism and other brain disorders

Credit: Laboratory of Developmental Neurobiology at The Rockefeller University

In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins–proverbial hands that reach out and greet nearby cells. And, like a creepily long handshake, surface molecules

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Bioengineer.org: Higher depression risk in young adulthood associated with autism spectrum disorders

Bioengineer.org: Higher depression risk in young adulthood associated with autism spectrum disorders

Bottom Line: Autism spectrum disorders (ASD), especially without an accompanying intellectual disability, were associated with greater risk for depression in young adulthood compared with the general population and siblings without ASD.

Why The Research Is Interesting: Mental health problems, including depression, are considered common in people with ASD. Understanding depression

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Bioengineer.org: A mechanism underlying activity of cancer and autism associated proteins was discovered

Bioengineer.org: A mechanism underlying activity of cancer and autism associated proteins was discovered

Credit: Sergey Dmitriev

An international team of researchers has determined the function of a new family of proteins associated with cancer and autism. The results have been published in Molecular Cell. The study was supported by a grant from the Russian Science Foundation (RSF).

To make our body function

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Bioengineer.org: Discovery of a key protein involved in the development of autism

Bioengineer.org: Discovery of a key protein involved in the development of autism

Credit: IRB Barcelona

Most individuals with autism spectrum disorder cannot be distinguished by physical traits or by severe neurological symptoms. In fact, these cases can be identified only on the basis of certain behaviour, namely their obsessive focus on certain activities, and difficulties with social communications and interactions. Recent years

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Bioengineer.org: Study IDs important role for specific gene in 16p11.2 deletion autism

Bioengineer.org: Study IDs important role for specific gene in 16p11.2 deletion autism

Credit: Picower Institute for Learning and Memory

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT’s Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate

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Bioengineer.org: Whole genome sequencing identifies new genetic signature for autism

Bioengineer.org: Whole genome sequencing identifies new genetic signature for autism

Credit: Turner et al./Cell 2017

Autism has genetic roots, but most cases can’t be explained by current genetic tests.

Now, patterns found in autistic children’s genomes – the complete set of genetic instructions inside cells – have revealed a new genetic signature for the disorder. The signature helps explain cases

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Bioengineer.org: Untapped region in brain cell offers goldmine of drug targets for new autism treatments

Bioengineer.org: Untapped region in brain cell offers goldmine of drug targets for new autism treatments

IMAGE: UCLA scientists discovered a treasure trove of drug targets for new autism therapies in this part of the cell.

Credit: Martin lab/UCLA

UCLA scientists have discovered that an overlooked region in brain cells houses a motherlode of mutated genes previously tied to autism. Recently published in Neuron, the finding

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Bioengineer.org: TSU is developing a new method for treating autism and memory disorder

Bioengineer.org: TSU is developing a new method for treating autism and memory disorder

Credit: TSU

Scientists at the Tomsk State University (TSU, Russia) are exploring myokines, proteins that are produced in the muscles during physical activities. It is found that these active agents enhance human cognitive function. Scientists plan to use this feature to correct conditions such as autism, hyperactivity, and memory disorders.

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Bioengineer.org: Faulty cell signaling derails cerebral cortex development, could it lead to autism?

Bioengineer.org: Faulty cell signaling derails cerebral cortex development, could it lead to autism?

Credit: Anton Lab, UNC School of Medicine

CHAPEL HILL, NC – As the embryonic brain develops, an incredibly complex cascade of cellular events occur, starting with progenitors – the originating cells that generate neurons and spur proper cortex development. If this cascade malfunctions – if one tiny protein doesn’t do

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Bioengineer.org: Study identifies new genetic risk factor for developing autism spectrum disorder

Bioengineer.org: Study identifies new genetic risk factor for developing autism spectrum disorder

Credit: (OHSU/John Valls)

Autism spectrum disorder affects approximately one out of every 68 children in the United States. Despite expansive study, the origin and risk factors of the complex condition are not fully understood.

To better understand the root causes, an international team led by researchers at OHSU in Portland,

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Bioengineer.org: Genes, ozone, and autism

Bioengineer.org: Genes, ozone, and autism

Credit: Penn State University

University Park, PA — A new analysis shows that individuals with high levels of genetic variation and elevated exposure to ozone in the environment are at an even higher risk for developing autism than would be expected by adding the two risk factors together. The study

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