Scientificamerican.com: Using Big Data to Hack Autism

It’s been 10 years since Michael Wigler had a breakthrough revelation in autism genetics—one that arguably launched the field as we know it.

In April 2007, Wigler and his then colleague, Jonathan Sebat, reported that ‘de novo’ mutations—those that arise spontaneously instead of being inherited—occur more often in people with autism than in

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